thymine dimer造句

• The tanning activator coumarin is known to induce thymine dimers ( cyclobutane pyrimidine dimers ).
• :The original poster should note that DNA damage such as thymine dimers can cause cancer.
• In general, cancers are caused by damage to DNA . UVA light mainly causes thymine-thymine dimers.
• UV DNA damage results in bulky DNA adducts-these adducts are mostly thymine dimers and 6, 4-photoproducts.
• The error is called a thymine dimer.
• This " thymine dimer " makes a bulge, and the distorted DNA molecule does not function properly.
• UV rays in the middle range can irreparably damage the complex DNA molecules in the cells producing thymine dimers making it a very potent mutagen.
• If added to a topical preparation of ascorbic acid and vitamin E, ferulic acid may reduce oxidative stress and formation of thymine dimers in skin.
• Although DNA is always susceptible to damage by ionizing radiation, the DNA molecule may also be damaged by radiation with enough energy to excite certain molecular bonds to form thymine dimers.
• However, it accurately replicates UV-damaged DNA; when thymine dimers are present, this polymerase inserts the complementary nucleotides in the newly synthesized DNA, thereby bypassing the lesion and suppressing the mutagenic effect of UV-induced DNA damage.
• One of the common mutations of DNA involves two adjacent thymines or cytosine, which, in presence of ultraviolet light, may form thymine dimers, causing " kinks " in the DNA molecule that inhibit normal function.
• Because of course the photon doesn't generally " energize " all the DNA in your nucleus and cause damage to it by some hazy mechanism afterward; it interacts with one specific thymine dimer or the like.
• For example, high energies can induce a double strand break while much more sedate chemical reactions like thymine dimers from even UV light can lead to the modification of a single base pair . talk ) 23 : 43, 8 November 2016 ( UTC)
• UVA also produces reactive oxygen species and these inflict other DNA damage, primarily single-strand breaks, oxidized pyrimidines and the oxidized purine 8-oxoguanine ( a mutagenic DNA change ) at 1 / 10th, 1 / 10th and 1 / 3rd the frequencies of UVA-induced thymine-thymine dimers, respectively.
• Dior laboratories have demonstrated in laboratory tests that the application of a Vitamin C derivative to a sample of isolated skin exposed to UV rays, reduces the level of thymine dimers ( photo-products of cell degeneration ), showing a protective effect of the vitamin against the damage of UV rays.
• UVA can generate highly reactive chemical intermediates, such as hydroxyl and oxygen radicals, which in turn can damage DNA . The DNA damage caused indirectly to skin by UVA consists mostly of single-strand breaks in DNA, while the damage caused by UVB includes direct formation of thymine dimers or other pyrimidine dimers, and double-strand DNA breakage.